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Patrick M Tarwater Selected Research

Central Nervous System Diseases (CNS Diseases)

1/2018Increased Microglial CSF1R Expression in the SIV/Macaque Model of HIV CNS Disease.
8/2015Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART.
12/2014Combination fluconazole/paroxetine treatment is neuroprotective despite ongoing neuroinflammation and viral replication in an SIV model of HIV neurological disease.
11/2013Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain.
6/2012Early minocycline treatment prevents a decrease in striatal dopamine in an SIV model of HIV-associated neurological disease.
7/2010Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA.
1/2008Natural host genetic resistance to lentiviral CNS disease: a neuroprotective MHC class I allele in SIV-infected macaques.
2/2006Platelet decline: an early predictive hematologic marker of simian immunodeficiency virus central nervous system disease.
3/200514-3-3 protein in CSF: an early predictor of SIV CNS disease.

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Patrick M Tarwater Research Topics

Disease

20Infections
09/2015 - 10/2002
9Central Nervous System Diseases (CNS Diseases)
01/2018 - 03/2005
6Encephalitis (Encephalitis, Rasmussen)
06/2012 - 01/2003
4Inflammation (Inflammations)
01/2022 - 07/2010
3Viremia
09/2015 - 06/2005
3Acquired Immunodeficiency Syndrome (AIDS)
07/2010 - 12/2004
2Anterior Cruciate Ligament Injuries
07/2016 - 09/2013
2HIV Infections (HIV Infection)
08/2015 - 02/2004
2Neurocognitive Disorders (Clerambault Syndrome)
12/2014 - 08/2013
2AIDS Dementia Complex
09/2007 - 10/2002
2Asymptomatic Infections
10/2006 - 10/2002
2Disease Progression
06/2005 - 09/2004
1Necrosis
01/2022
1Rupture
07/2016
1Nervous System Diseases (Neurological Disorders)
08/2015
1Neuroinflammatory Diseases
12/2014
1Peripheral Nervous System Diseases (PNS Diseases)
11/2011
1Cardiomyopathies (Cardiomyopathy)
04/2011
1Tics (Tic)
04/2011
1Heart Failure
04/2011
1Tachycardia (Tachyarrhythmias)
04/2011
1Neoplasms (Cancer)
02/2011
1Pneumocystis Infections
09/2010
1Human Influenza (Influenza)
07/2010
1Cognitive Dysfunction
06/2010
1Virus Diseases (Viral Diseases)
01/2007

Drug/Important Bio-Agent (IBA)

7RNA (Ribonucleic Acid)IBA
08/2013 - 01/2003
6Viral RNAIBA
01/2022 - 10/2002
6ChemokinesIBA
08/2013 - 02/2004
5Biomarkers (Surrogate Marker)IBA
07/2016 - 02/2006
5CytokinesIBA
08/2013 - 02/2004
3Interferon-gamma (Interferon, gamma)IBA
08/2013 - 01/2008
3Proteins (Proteins, Gene)FDA Link
04/2011 - 03/2005
3Messenger RNA (mRNA)IBA
07/2010 - 04/2006
2MicroRNAs (MicroRNA)IBA
08/2013 - 02/2011
2Chemokine ReceptorsIBA
08/2013 - 09/2010
2Interferon-betaIBA
07/2010 - 04/2006
2Interleukin-6 (Interleukin 6)IBA
07/2010 - 12/2009
2Viral DNAIBA
07/2010 - 10/2002
2DNA (Deoxyribonucleic Acid)IBA
01/2006 - 10/2002
1LigandsIBA
01/2018
1Macrophage Colony-Stimulating FactorIBA
01/2018
1CollagenIBA
07/2016
1Serotonin (5 Hydroxytryptamine)IBA
08/2015
1KynurenineIBA
08/2015
13-hydroxykynurenineIBA
08/2015
1Tryptophan (L-Tryptophan)FDA Link
08/2015
1Quinolinic AcidIBA
08/2015
1Fluconazole (Zonal)FDA LinkGeneric
12/2014
1Paroxetine (Paxil)FDA LinkGeneric
12/2014
1MaravirocFDA Link
11/2013
1Interferon Type IIBA
08/2013
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
08/2013
13,4-Dihydroxyphenylacetic AcidIBA
06/2012
1Minocycline (Cyclops)FDA LinkGeneric
06/2012
1Cardiotonic Agents (Cardiac Stimulants)IBA
04/2011
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
04/2011
1salicylhydroxamic acid (SHAM)IBA
04/2011
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
03/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2010
1Glial Fibrillary Acidic ProteinIBA
07/2010
1Atazanavir Sulfate (Reyataz)FDA Link
07/2010
1Tenofovir (Viread)FDA Link
07/2010
1Saquinavir (Invirase)FDA Link
07/2010
1Integrase InhibitorsIBA
07/2010
1indolamineIBA
07/2010
1InterferonsIBA
07/2010
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
06/2010
1CCAAT-Enhancer-Binding Protein-betaIBA
12/2009
1Protein Isoforms (Isoforms)IBA
12/2009
1Forkhead Transcription Factors (Forkhead Box Proteins)IBA
04/2008
1antineoplaston A10 (A 10)IBA
01/2008
1Toll-Like Receptor 3IBA
01/2008
1SIV envelope protein gp41IBA
01/2007
1Hemoglobins (Hemoglobin)IBA
02/2006
1Dihydrotachysterol (AT 10)IBA
01/2006
114-3-3 Proteins (14-3-3 Protein)IBA
03/2005
1Neurotransmitter Agents (Neurotransmitter)IBA
03/2005
1Mitogen-Activated Protein KinasesIBA
02/2004

Therapy/Procedure

6Therapeutics
09/2015 - 09/2004
4Highly Active Antiretroviral Therapy (HAART)
09/2015 - 12/2004